May 23 2023
A research group led by Associate Professor DOMON Hisanori and Professor TERAO Yutaka of the Division of Microbiology and Infectious Diseases, Graduate School of Medical and Dental Sciences, Niigata University discovered that azithromycin and erythromycin, macrolides drugs1, prevent exacerbation of inflammation by suppressing the production of inflammation inducers released by Streptococcus pneumoniae. The research was published in the online version of the US scientific journal Microbiology Spectrum on May 16, 2023.
1. An antibacterial agent that suppresses protein synthesis in bacteria.
Journal:?Microbiology Spectrum
Title: Macrolides decrease the proinflammatory activity of macrolide-resistant Streptococcus pneumoniae
Authors: Hisanori Domon, Satoru Hirayama, Toshihito Isono, Karin Sasagawa, Fumio Takizawa, Tomoki Maekawa, Katsunori Yanagihara, Yutaka Terao
doi: 10.1128/spectrum.00148-23
Elevated cdc42 activity is a key initiation event leading to proteinuria. -Regulation of cdc42 activity could be a promising therapy for nephrotic syndrome.-
Temozolomide and radiation treatment lead to dramatic tumor shrinkage and improvement of hearing in an adult brainstem glioma patient with a rare IDH2 mutation
Fertilizable rat sperm produced in a mouse body by blastocyst complementation